Results 131 to 140 of about 397,094 (306)

Health sector reform and reproductive health in Latin America and the Caribbean: strengthening the links

Bulletin of the World Health Organization, 2000
Many countries in Latin America and the Caribbean (LAC) are currently reforming their national health sectors and also implementing a comprehensive approach to reproductive health care.
A. Langer, G. Nigenda, J. Catino
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Law, Medicine, and Forensic Science: A Comprehensive Medico-Legal Analysis of Ethics, Liability, Mental Health, Reproductive Technologies, and Medical Negligence Ganesh Shrirang Nale (Central University of Haryana) & Dr. Priyanka Sambhaji Jadhavar (Shivaji University, Kolhapur)

GANESH SHRIRANG SATARKAR, Sambhaji Jadhavar Dr. Priyanka   +1 more
openalex   +1 more source

Abstracts for 2017 Foundation for Reproductive Medicine Translational Reproductive Biology and Clinical Reproductive Endocrinology Conference [PDF]

, 2017
A Bernabéu, J A Ortíz, Belén Lledó, R Morales, Elena Fernández, Jorge Ten, Rafael Bernabéu, Eusebio S. Pires, John C. Herr, Ryan Miller, Chin‐Fu Chen, Jane M. DeLuca, Henry Malter   +12 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Extracellular vesicles in reproductive medicine: from "animal-led" to "plant-enabled". [PDF]

Front Cell Dev Biol
Pan K, Ju W, Wang Y, Zhang Q, Wang R, Jiang X, Zhao S.   +6 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Survey of U.S. reproductive medicine clinicians' attitudes on polygenic embryo screening. [PDF]

NPJ Genom Med
Furrer RA, Barlevy D, Gandhi A, Carmi S, Lencz T, Pereira S, Lázaro-Muñoz G.   +6 more
europepmc   +1 more source

Preliminary Screening of Traditional Medicine Against Porcine Reproductive and Respiratory Syndrome Virus [PDF]

YAPING CHEN, XINYI ZHAO, Wenshuang Chen, Song Xinqi, Yang Li, RUOYU ZHAO, Meixia Song, BINGBING ZHANG, DONGYU LIU   +8 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source