Results 191 to 200 of about 397,094 (306)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Hereditary Neuromuscular Disorders in Reproductive Medicine. [PDF]

Genes (Basel)
Luglio A, Maggi E, Riviello FN, Conforti A, Sorrentino U, Zuccarello D.   +5 more
europepmc   +1 more source

CHRONIC ENDOMETRITIS AS A CHALLENGE IN MODERN REPRODUCTIVE MEDICINE: DIAGNOSTIC AND PATHOGENETIC ASPECT

Artem Malanchuk, Ruslana Khrustavka, Myroslav Fedorovych, Л. М. Маланчук, Viktoriia Martyniuk, U. Ya. Franchuk, С. Л. Маланчук   +6 more
openalex   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Effect of interprofessional education on interprofessional professionalism behavior and Self-efficacy in communication among the infertility and reproductive medicine team. [PDF]

BMC Med Educ
Dashti S, Heidari AS, Keshmiri F.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Global Andrology Forum Clinical Guidelines on the Relevance of Sperm DNA Fragmentation in Reproductive Medicine. [PDF]

World J Mens Health
Çayan S, Farkouh A, Agarwal A, Atmoko W, Wyns C, Arafa M, Zini A, Shah R, Alipour H, Chung E, Saleh R, Pinggera GM, Konstantinidis C, Al Hashimi M, Pescatori E, Rambhatla A, Toprak T, Calogero AE, Gül M, Park HJ, Altay B, Falcone M, Rashed A, Le TV, Bahar F, Shatylko T, Görür S, El-Sakka AI, Saylam B, Sarikaya S, Smith RP, Boeri L, Efesoy O, Ceyhan E, Russo GI, Ozer C, Ho CCK, Gungor ND, Özlü DN, Molina JMC, Musa MU, Tsujimura A, Gokalp F, Mohamed MS, Okada K, Khalafalla K, Kuroda S, Binsaleh S, Motawi AT, Shamohammadi I, Mogharabian N, Manh MT, Taha EA, Makarounis K, Mak SK, Shedeed SA, Thomas C, Mostafa T.   +57 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Advances in Reproductive Medicine

Journal of the Royal College of Physicians of London, 1991
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source