Results 211 to 220 of about 387,167 (258)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Construction, validation, and nitrogen nutrition diagnosis of a critical nitrogen concentration model for cotton. [PDF]

Front Plant Sci
Qin Y, Feng W, Chen J, Zheng C, Leng Y, Wang L, Zhang L, Nie T.   +7 more
europepmc   +1 more source

Correction: a novel reproductive mode in frogs: a new species of fanged frog with internal fertilization and birth of tadpoles. [PDF]

PLoS One, 2015
PLOS ONE Staff.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

First clinical use of the kisspeptin analog TAK-683 in the treatment of a follicular cyst in a goat: case report. [PDF]

Vet Res Commun
Uyanık G, Yüksel M, Kara F, Gözer A, Abay M.   +4 more
europepmc   +1 more source

A novel reproductive mode in frogs: a new species of fanged frog with internal fertilization and birth of tadpoles. [PDF]

PLoS One, 2014
Iskandar DT, Evans BJ, McGuire JA.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence. [PDF]

Environ Microbiol
Brinker P, Salles JF, Beukeboom LW, Fontaine MC.   +3 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Developmental, regenerative, and behavioral dynamics in acoel reproduction. [PDF]

Elife
Chandra V, Tseng SE, Kann AP, Bolanos DM, Srivastava M.   +4 more
europepmc   +1 more source