Results 241 to 250 of about 390,311 (303)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Construction, validation, and nitrogen nutrition diagnosis of a critical nitrogen concentration model for cotton. [PDF]

Front Plant Sci
Qin Y, Feng W, Chen J, Zheng C, Leng Y, Wang L, Zhang L, Nie T.   +7 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

First clinical use of the kisspeptin analog TAK-683 in the treatment of a follicular cyst in a goat: case report. [PDF]

Vet Res Commun
Uyanık G, Yüksel M, Kara F, Gözer A, Abay M.   +4 more
europepmc   +1 more source

Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence. [PDF]

Environ Microbiol
Brinker P, Salles JF, Beukeboom LW, Fontaine MC.   +3 more
europepmc   +1 more source

Developmental, regenerative, and behavioral dynamics in acoel reproduction. [PDF]

Elife
Chandra V, Tseng SE, Kann AP, Bolanos DM, Srivastava M.   +4 more
europepmc   +1 more source

Association between endometriosis and adverse reproductive and perinatal outcomes in women undergoing assisted reproductive technology: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Wei Y, Xiao X, Wu X, Xie C, Li T.
europepmc   +1 more source

Allometry and phylogeny of within-diaspore biomass allocation: A global analysis. [PDF]

Biol Lett
Cruz AR, Enquist BJ.
europepmc   +1 more source