Results 61 to 70 of about 387,167 (258)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Egg clutch structure of Rhinella rumbolli (Anura: Bufonidae), a toad from the Yungas of Argentina, with a review of the reproductive diversity in Rhinella [PDF]
, 2015 Rhinella rumbolli is a poorly known, medium-sized toad endemic to the Yungas of Argentina. Recent fieldwork allowed observing its peculiar oviposition mode, which is described in this paper.
Baldo, Juan Diego +3 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Making the Co-operative School a Challenge Alternative: Social Reproduction Theory Revisited [PDF]
, 2017 While co-operative schools are different, there are different kinds of different schools. This essay examines the type of alternative co-operative schools are, using distinctions Philip A. Woods draws from Maori philosophy of education.
David Backer
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Reproductive inequalities in the acanthocephalan Corynosoma cetaceum: looking beyond "crowding" effects [PDF]
, 2018 Background: At present, much research effort has been devoted to investigate overall (average) responses of parasite populations to specific factors, e.g., density-dependence in fecundity or mortality. However, studies on parasite populations usually pay
Aznar Avendaño, Francisco Javier +5 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Psychoanalysis and politics: Juliet Mitchell then and now [PDF]
, 2000 Feminism and psychoanalysis have been in constant dialogue over the last four decades, and Juliet Mitchell has played a critical role in instigating and shaping that conversation.
Segal, Lynne
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Transcriptomic and proteomic analyses of seasonal photoperiodism in the pea aphid
BMC Genomics, 2009 Background Aphid adaptation to harsh winter conditions is illustrated by an alternation of their reproductive mode. Aphids detect photoperiod shortening by sensing the length of the night and switch from viviparous parthenogenesis in spring and summer ...
Gauthier J-P +11 more
doaj +1 more source