Results 91 to 100 of about 537,641 (265)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Adverse Effects of Broflanilide on the Demographic Parameters and Life Cycle of the Egg Parasitoid Trichogramma pintoi

ISPEC Journal of Agricultural Sciences
Broflanilide as a meta-diamide insecticide can effectively suppress diverse herbivorous insect pests including both chewing and piercing-sucking species.
Adil TONĞA
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Associations of personal care products use with reproductive outcomes of IVF/ICSI treatment

Frontiers in Endocrinology
IntroductionPersonal care products (PCPs) contain a number of endocrine-disrupting chemicals (EDCs) that could potentially affect the reproductive function in women of childbearing age.
Qing-Chun Guo, Wen Yao, Chong Liu, Tao-Ran Deng, Juan Li, Hong-Mei Liao, Wen-Qu Tian, Yi Wang, Yao-Yao Du, Yu-Feng Li   +9 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Trend of cancer mortality of the female reproductive system in China from 2005 to 2018 and prediction to 2035: A log-linear regression and Bayesian age-period- cohort analysis.

PLoS ONE
ObjectiveIn recent years, the number of deaths from female reproductive system cancer in China has been continuously increasing, and there are relatively few studies on their mortality situation.
Lili Xu, Ting Zhao, Xin-Hua Wang, Guang-Sheng Wu, Weixia Nong   +4 more
doaj   +1 more source

Integrated analysis of reproductive performance, herd structure, and farmer characteristics in tropical smallholder beef cattle systems

Jurnal Ilmu Peternakan dan Veteriner Tropis
Sustainable growth of beef cattle production in tropical smallholder systems depends on the interaction between reproductive efficiency, herd structure, and farmer capacity. This study aimed to provide an integrated analysis of reproductive performance,
Yendraliza Yendraliza, Rafida Rafida, Rido Setiawan   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source