A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Medroxyprogesterone acetate vs. GnRH antagonist for preventing premature LH surge during ovarian stimulation in assisted reproductive technology: a retrospective cohort study. [PDF]
Jimenez MM +3 more
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
The Impact of Feeding Organic Trace Minerals Using Advanced Chelate Technology on Reproductive Efficiency and Blood Parameters in Ghezel Ewes. [PDF]
Vatankhah S +6 more
europepmc +1 more source
Effects of selected nuts on the biology of Trogoderma granarium Everts. [PDF]
Khan HAA, Bukhari M.
europepmc +1 more source
Fertility Preservation Strategies in Women with Pelvic Gynecologic Malignancies Undergoing Multimodal Oncologic Treatment: A Systematic Review. [PDF]
Dadas Y +7 more
europepmc +1 more source
Scaling law links plant growth variation to grain yield in wheat stands. [PDF]
Golan G +6 more
europepmc +1 more source
Transforming Small Ruminant Productivity Through a Farm Service Delivery Model: Evidence from a Pilot Study in Saudi Arabia. [PDF]
Swaminathan M +5 more
europepmc +1 more source
Effect of Probiotic Supplementation on Reproductive Outcomes of Women With Polycystic Ovary Syndrome Who Are Candidates for Intrauterine Insemination: A Randomized, Double-Blind, Placebo-Controlled Trial. [PDF]
Behroozilak T +2 more
europepmc +1 more source

