Results 161 to 170 of about 81,621 (250)

Is Our Post-<i>Skrmetti</i> World Like a Post-<i>Dobbs</i> World?: Lessons from the Fight for Reproductive Rights. [PDF]

Dela J Public Health
Brickner M.
europepmc   +1 more source

Preserving the Reproductive Rights of Girls and Women in the Era of COVID-19: The Need for a Least Restrictive Solution. [PDF]

Am J Bioeth, 2020
Ott MA, Bernard C.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Impact of limiting reproductive rights of pregnant individuals with cancer in the United States. [PDF]

Gynecol Oncol
Aryasomayajula C, Stewart C, Eakin C, Reiser H, Chow S, Kapp DS, Chan JK, Liao CI.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Decrease in reproductive desires among non-parent heterosexual women during the COVID-19 pandemic in Poland: the role of epidemiological stress, socioeconomic status, and reproductive rights. [PDF]

Front Public Health
Marcinkowska UM, Kasparek KK, Zabdyr-Jamróz M, Kozłowska M, Nenko I.   +4 more
europepmc   +1 more source

Women's Reproductive Rights Policies and Adverse Birth Outcomes: A State-Level Analysis to Assess the Role of Race and Nativity Status. [PDF]

Am J Prev Med, 2020
Sudhinaraset M, Vilda D, Gipson JD, Bornstein M, Wallace ME.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

COVID-19 and Female Fertility: An Observational Prospective Multicenter Cohort Study: Upholding Reproductive Rights in Emergency Circumstances. [PDF]

Diagnostics (Basel)
Gullo G, Lopez A, Loreto C, Cucinella G, La Verde M, Andrisani A, Burgio S, Carotenuto R, Ganduscio S, Baglio G, Billone V, Perino A, De Franciscis P, Marinelli S.   +13 more
europepmc   +1 more source