Results 51 to 60 of about 105,952 (293)

From the Grassroots to the Oireachtas: Abortion Law Reform in the Republic of Ireland [PDF]

open access: yesHealth and Human Rights, 2019
In 1983, voters inserted the Eighth Amendment into Ireland’s constitution, equating the right to life of a fetus with that of a pregnant person. Hundreds of thousands of women were forced overseas to access basic health care and thousands more were ...
Anna Carnegie, Rachel Roth
doaj  

Breaking Ground 2018: Treaty Monitoring Bodies on Reproductive Rights [PDF]

open access: yes, 2018
Breaking Ground 2018: Treaty Monitoring Bodies on Reproductive Rights summarizes the jurisprudence from United Nations treaty monitoring bodies (TMBs) on reproductive rights, particularly the standards on reproductive health information and contraception,

core  

Reproducing Rights: The Intersection of Reproductive Justice and Human Rights

open access: yes, 2017
This Article argues that reproductive justice writings, by relying on human rights arguments, may perpetuate a limited vision for global justice—one that contradicts the movement’s core commitments and detracts from the change that the movement’s ...
Rebouché, Rachel
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Reproductive Technologies and Women\u27s Rights. [PDF]

open access: yes, 1992
Fay Cooper spoke on reproductive technologies and rights, and looked into whose interests are really being met, and the threat of separating mother and ...
SFU Women\u27s Studies Department   +1 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Advancing women's reproductive and sexual health rights: using the International Human Rights system

open access: yes, 2000
Often the primary barriers to improving women's health are rooted in socio-economic, legal, and cultural factors. Women are generally assigned subordinate status in terms of economic power, decision making, and options regarding education, work, and ...
Merali, Isfahan
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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