From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Assessing the role of key genes involved in the reproductive success of the honey bee parasite Varroa destructor. [PDF]
Muntaabski I +7 more
europepmc +1 more source
The transition from cryogenic distillation to polymeric sorbents for light hydrocarbon purification is crucial for energy and environmental sustainability. The polymeric sorbents are engineered to separate gas mixtures based on their specific properties.
Kelechi Festus +9 more
wiley +1 more source
Impact of fragmented habitats on reproductive success in dominant shrubs: natural selection on floral display and pollinator visitation. [PDF]
Chen M, Wang ZJ, Ma XJ, Zhao XY.
europepmc +1 more source
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi +5 more
wiley +1 more source
Pathogen-induced alterations in fine-scale movement behaviour predict impaired reproductive success. [PDF]
Grabow M +11 more
europepmc +1 more source
Electrolyte Design for Fast‐Charging Lithium‐Based Batteries
A decade of progress in fast‐charging electrolytes for lithium batteries is reviewed. Electrolyte design strategies spanning solvents, salts, additives, and advanced systems, such as localized high‐concentration electrolytes (LHCEs), are summarized. Advanced diagnostic tools for lithium plating and interphase chemistry are discussed, with perspectives ...
Chen Liu, Zehao Cui, Arumugam Manthiram
wiley +1 more source
The interplay between local biodiversity floral odours and reproductive success varies across different population sizes of <i>Cypripedium calceolus</i>. [PDF]
Haouzi M +6 more
europepmc +1 more source
This work prototypes a carbon nanotube‐based analog tensor core that performs in‐memory, parallel visual processing. Integrating non‐volatile memories and compact circuits, the core enables high‐speed analog matrix multiplications and can demonstrate accurate three dimensional (3D) spatial transformation and edge detection. With lightweight design, the
Jingfang Pei +11 more
wiley +1 more source
Effects of Urbanization on Flowering Phenology, Pollination, and Reproductive Success in the Chiropterophilous Tropical Tree <i>Ceiba pentandra</i>. [PDF]
Dzul-Cauich HF, Munguía-Rosas MA.
europepmc +1 more source

