Results 61 to 70 of about 626,055 (306)
NGF, EPO, and IGF-1 in the Male Reproductive System
Several studies have demonstrated interesting results considering the implication of three growth factors (GFs), namely nerve growth factor (NGF), erythropoietin (EPO), and the insulin-like growth factor-I (IGF-1) in the physiology of male reproductive ...
Chrysovalanto Staneloudi +3 more
core +1 more source
Impact of heavy metals on the female reproductive system [PDF]
, 2015 Introduction It has been recognized that environmental pollution can affect the quality of health of the human population. Heavy metals are among the group of highly emitted contaminants and their adverse effect of living organisms has been widely ...
Piotr Rzymski +16 more
core +1 more source
An integrated drug repositioning analysis identifies rosiglitazone as a treatment for sarcopenia
Communications BiologyAge-related sarcopenia is a growing global health challenge with no approved pharmacotherapies. Here, we integrate network-based drug repurposing and Mendelian randomization to identify rosiglitazone, a PPARγ agonist used in diabetes, as a potential ...
Shuang Liang +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2018 The reproductive system is a body system that shows pronounced changes in structure and function across the lifespan. Reproductive disorders can develop rapidly and may have acute, serious and life-threatening consequences.No Full ...
Coyne, E, De-Vitry Smith, SA
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Reproduction is the only certain constant within animals and maintaining the integrity of this process is key to ensuring survival of the species. However, male fertility rates in the Western world are in decline and the use of assisted reproductive ...
Ross, Bryony Louise
core +1 more source
Current assisted reproduction treatment practices from an Islamic perspective
, 2007 Islam encourages new developments for the benefit of Man and Society. It does not, however, approve such developments if they introduce legal, moral, and spiritual problems and hazards for humanity. Thus Islam does not have reservations for biological or
core +1 more source