Results 191 to 200 of about 475,651 (353)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
The Resilience Scale in Portuguese Adults under Assisted Reproductive Techniques. [PDF]
Int J Environ Res Public Health, 2022 Romeiro J +3 more
europepmc +1 more source
The prognostic value of glycodelin and macrophage-colony stimulating factor from the cervico-vaginal secretions and the serum as an implantation marker in the assisted reproductive techniques [PDF]
, 2010 Hulusi Bülent Zeyneloğlu +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Human Papillomavirus Infection Is an Unresolved Challenge in Assisted Reproductive Techniques. [PDF]
J Reprod Infertil, 2022 Sadeghi MR.
europepmc +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Knowledge and Attitude of Infertile People toward Assisted Reproductive Techniques in Hamadan, Iran. [PDF]
Med J Islam Repub Iran, 2022 Rabiei N +4 more
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Insulin-like growth factor-1 on cycle day 2 and assisted reproductive techniques outcome: A cross-sectional study. [PDF]
Int J Reprod Biomed, 2023 Abbasi F, Davar R, Shamsi F, Dashti S.
europepmc +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source