Results 81 to 90 of about 216,273 (311)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Trends and factors associated with skilled birth attendance in a post-Ebola context: DHS Guinea 2018

Journal of Public Health in Africa
Background: In Guinea, the 2013–2015 Ebola epidemic profoundly affected maternal health service use. The frequency of births attended by skilled health professionals in the post-Ebola context remains under-documented.
Madeleine Toure, Fanta Barry, Tiany Sidibe, Sadan Camara, Ramata Diallo, Kaba Saran Keita, Maimouna Balde, Bienvenu Salim Camara, Karifa Kourouma, Mamadou Dioulde Balde   +9 more
doaj   +1 more source

2012 Assisted Reproductive Technology National Summary Report [PDF]

The data for this national report come from the 456 fertility clinics in operation in 2012 that provided and verified data on the outcomes of all ART cycles started in their clinics. Of the 176,247 ART cycles performed in 2012 at these reporting clinics,

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

2011 Assisted Reproductive Technology National Summary Report [PDF]

The data for this national report come from the 451 fertility clinics in operation in 2011 that provided and verified data on the outcomes of all ART cycles started in their clinics.

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

2018 Assisted Reproductive Technology National Summary Report [PDF]

The data for this national report come from the 456 US fertility clinics in operation in 2018 that provided and verified data on the outcomes of all ART cycles started in their clinics.

core  

Experimental reduction of intromittent organ length reduces male reproductive success in a bug [PDF]

, 2015
This work was funded by the Natural Environment Research Council DTG PHD studentships to L.R.D., E.R.B.-S. and E.V.G., and an 1851 Royal Commission Research Fellowship to I.A.R.It is now clear in many species that male and female genital evolution has ...
Burdfield-Steel, Emily R., Shuker, David M, Imran A. Rahman, Dougherty, Liam R, Liam R. Dougherty, E. V. (Ginny) Greenway, Dougherty, Liam R., Greenway, E V Ginny, Rahman, Imran A., David M. Shuker, Emily R. Burdfield-Steel, Greenway, E. V. (Ginny), Burdfield-Steel, Emily R, Shuker, David M.   +13 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Illegal yet ongoing: surrogacy through the moral prism of urban Chinese women in Nanjing

Salud Colectiva
How urban Chinese women understand and morally evaluate surrogacy remains an insufficiently explored area, despite the persistence of this practice in clandestine forms under a strict legal ban in China.
Zhenkang LI
doaj   +1 more source