Results 121 to 130 of about 595,021 (365)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

L’expérience des femmes quadragénaires en AMP : les seuils de la temporalité procréative, de la fertilité et de l’infertilité en question

open access: yesEnfances, Familles, Générations, 2018
Research Framework : There has been a significant increase in age of first maternities in Euro-American societies. This has increasingly led women to turn to assisted reproduction technology (ART) to help with infertility caused by the “natural ...
Manon Vialle
doaj  

The MacArthur Foundation in Nigeria: Report on Activities 2009 [PDF]

open access: yes, 2009
Highlights the foundation's work to build the scientific research capacity of Nigerian universities, to reduce maternal mortality and improve sexual and reproductive health, and to advance human rights.

core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Failure to collect oocytes in assisted reproductive technology: a retrospective [PDF]

open access: bronze, 1998
G. L. Driscoll   +6 more
openalex   +1 more source

The MacArthur Foundation in Nigeria: Report on Activities 2006 [PDF]

open access: yes, 2006
Contains president's message, foundation information, information on focus areas and programs in Nigeria, grantee profiles, lists of recent grants, and lists of board members and ...

core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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