Results 201 to 210 of about 7,716,482 (438)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

The State of the Science of Natural Family Planning Fifty Years after Humane Vitae: A Report from NFP Scientists’ Meeting Held at the US Conference of Catholic Bishops, April 4, 2018 [PDF]

open access: yes, 2018
A one-day meeting of physicians, professional nurses, and scientists actively involved in Natural Family Planning (NFP) research was held to review the state of the science of NFP and consider future priorities.
Fehring, Richard, Manhart, Michael D.
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

FACTORS INFLUENCING RATES OF ADOPTION OF TRICHOMONIASIS VACCINE BY NEVADA RANGE CATTLE PRODUCERS [PDF]

open access: yes
Tritrichimonas foetus vaccine has been marketed since 1989 to combat the trichomoniasis disease that causes reproductive failure and considerable economic loss to Nevada ranchers.
Bhattacharyya, Arunava   +3 more
core   +1 more source

Late reproductive age and modern technology [PDF]

open access: yesГинекология, 2019
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doaj   +1 more source

Psychosocial discontinuities introduced by the new reproductive technologies [PDF]

open access: bronze, 1998
Robert J. Snowden
openalex   +1 more source

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