Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Conception and Concern: A Review of Breast Cancer Risk in Assisted Reproductive Technology. [PDF]
Guo Z+9 more
europepmc +1 more source
Electroejaculation and assisted reproductive technologies in the treatment of anejaculatory infertility [PDF]
Dana A. Ohl+7 more
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Establishing a predictive model for ectopic pregnancy risk following assisted reproductive technology. [PDF]
Li J+6 more
europepmc +1 more source
Comparison of implantation and pregnancy rates in African American and white women in an assisted reproductive technology practice [PDF]
John E. Nichols+3 more
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Ethical Imperatives in the Integration of Artificial Intelligence in Assisted Reproductive Technology. [PDF]
Nair N, Badge AK, Mishra V, Bankar NJ.
europepmc +1 more source
The future of international registries for assisted reproductive technologies [PDF]
Jean Cohen
openalex +1 more source