Results 191 to 200 of about 449,621 (314)

Surveillance-based evidence: elimination of schistosomiasis as a public health problem in the Peoples' Republic of China. [PDF]

open access: yesInfect Dis Poverty, 2020
Xu J   +15 more
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao   +8 more
wiley   +1 more source

Hydrogel Stack‐Tailored Logics and High‐Fidelity Multimodal Sensors Promoted by Precisely Evaluated Ionic Migration

open access: yesAdvanced Science, EarlyView.
Inspired by biological ion transport, this work introduces self‐powered multifunctional sensors utilizing tailored hydrogel stacks. Optimizing ionic migration with MXenes and carbon nanotubes achieves high‐performance energy harvesting and unique logic circuit functionality.
Haoran Chen   +9 more
wiley   +1 more source

Current Status of Schistosomiasis Control and Prospects for Elimination in the Dongting Lake Region of the People's Republic of China. [PDF]

open access: yesFront Immunol, 2020
Li FY   +9 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

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