Results 71 to 80 of about 4,546,789 (273)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
1993 Juvenile Justice and Delinquency Prevention Act Compliance Monitoring Report [PDF]
, 1994 The Juvenile Justice and Delinquency Prevention Act (JJDPA) mandates removal of status offenders and nonoffenders from secure detention and correctional facilities, sight and sound separation of juveniles and adults, and removal of juveniles from adult ...
Atwell, Cassie +2 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
InRhode Filled Requests for 2009 [PDF]
, 2009 InRhode borrowing request for ...
Souto, Ruth E..
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Lexical and Grammatical Means of Distancing Strategy Performed in American Political Discourse
Journal of Language and Education, 2017 This article provided a survey of the English lexis and grammar constructions that serve to realize communicative intention of request aimed at distance enforcement in the American political discourse.
Vera Karnyushina, Alina Makhina
doaj +1 more source
Letter from a Canadian Supporter to Geraldine Ferraro [PDF]
, 1984 Letter from a Canadian supporter to Geraldine Ferraro. Author request an autograph. Letter has handwritten notes.https://ir.lawnet.fordham.edu/vice_presidential_campaign_correspondence_1984_international/1223/thumbnail ...
Ferraro, Geraldine
core +1 more source
Finite Magnetic Flux Tube as a Black & White Dihole
, 1994 A finite-length magnetic vortex line solution is derived within the context of (4-dim) dilaton gravity. We approach the Bonnor metric at the Einstein-Maxwell limit, and encounter the "flux tube as (Euclidean) Kerr horizon" at the Kaluza-Klein level ...
Aharon Davidson +26 more
core +1 more source