Results 61 to 70 of about 669,285 (280)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2011 Background Junior physicians are sometimes sent in ambulances with critically ill patients who require urgent transfer to another hospital. Unfamiliar surroundings and personnel, time pressure, and lack of experience may imply a risk of insufficient ...
Christensen Erika F +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Western Journal of Emergency Medicine, 2012 Introduction: Drug-seeking behavior (DSB) in the emergency department (ED) is a very commonproblem, yet there has been little quantitative study to date of such behavior.The goal of this study wasto assess the frequency with which drug seeking patients ...
Sean M. Curry +3 more
doaj
Picketing for Area Standards: An Exception to Section 8(b)(7) [PDF]
, 1968 A union\u27s picketing for area standards, requesting a non-union employer to provide the prevailing employment benefits offered by unionized operations in the locale, has been held by the National Labor Relations Board to be non-recognitional and hence ...
core +1 more source
An Energy Packet Switch for Digital Power Grids
, 2018 We propose the design and electrical description of an energy packet switch for forwarding and delivery of energy in digital power grids in this paper.
Grebel, Haim +5 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An algebraic basis for specifying and enforcing access control in security systems [PDF]
, 2000 Security services in a multi-user environment are often based on access control mechanisms. Static aspects of an access control policy can be formalised using abstract algebraic models.
Pahl, Claus
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Extradition Process in Transnasional Criminal Act to Find Perpetrators
Mimbar, 2016 In some research, it is elaborated that the process of extradition, MLA, Good Mutual Relation are conducted between governments represented by central authority from each state, meanwhile the process of Handing-Over is conducted by police (Ncb-Interpol ...
Muhamad Rakhmat
doaj