Results 91 to 100 of about 771,553 (295)
Summary of FY 1972 Funding Requests for Scientists-Astronauts
Summary of FY 1972 Funding Requests for Scientists and ...
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
gCube 4.0.0 - Species Tree Plugin Requests v. 1.0.0
<p> <br> The gCube System - Species TM Requests<br> ----------------------<br> <br> This work has been partially supported by the following European projects: DILIGENT (FP6-2003-IST-2), D4Science (FP7-INFRA-2007-1.2.2), < ...
Valentina Marioli +1 more
core +1 more source
Business students’ email requests: pragmatic production and perception of power and social distance
This study investigates Business and Administration students’ pragmatic production and perception of high-imposition email requests. Thirty L1 Spanish students with a high proficiency level in English wrote four requestive emails by means of Discourse ...
Tabita Gómez Rubio +1 more
doaj
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
(In)formal Requests in Students’ Emails in an Academic Context
This paper aims to provide an overview of the rhetorical strategies found in university students’ emails when they write to faculty members. The analysis is based on a self-compiled corpus of 100 emails written in English and sent to the author by the ...
Vesna Lazović
doaj +1 more source

