Results 191 to 200 of about 195,377 (266)

Investigations for Bronchiolitis in Infants: An Overview of Reviews and Systematic Review of Primary Studies. [PDF]

Pediatr Pulmonol
Loveys K, Borland ML, Oakley E, Babl FE, Cotterell E, Harrison G, Haskell L, O'Brien S, Tavender EJ, Wilson CL, Dalziel SR, Paediatric Research in Emergency Departments International Collaborative (PREDICT) network.   +11 more
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Public coverage of Long-Term Care in the post-COVID period: strengthening systems vs cost-containment. [PDF]

Public Policy Aging Rep
Comas-Herrera A, Salehi N, Chaverri-Carvajal A, Aaltonen M, Akkan B, Bottery S, Browne J, Cheshire-Allen M, Dunham M, Dunsmore M, Erdoğan Cansu C, Famira-Mühlberger U, Fenech MA, Forma L, Fransz-Myers M, Grigoras V, Gubert E, Hamandi A, Hlebec V, Hrast MF, Johansson L, Kantaris M, Kim H, Knapp D, Nies H, Perobelli E, Ping R, Potočnik T, Rajagopalan J, Sultana R, Trabut L, Vilaplana-Prieto C, Villalobos Dintrans P, Wachs D, Watson K, Wittenberg R, Zalakain J.   +36 more
europepmc   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Aggressive Nutrition Therapy in a Rehabilitation Hospital for Severe Tachypnoea and Profound Weight Loss With Interstitial Lung Disease: A Case Report. [PDF]

Respirol Case Rep
Morimoto Y, Yanase T, Matsuo T, Ohtsubo T, Tokihisa K, Shinbo A, Miyamoto K, Ueno K, Kozawa S.   +8 more
europepmc   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

The Adjunctive Role of Dynamic Systemic Inflammation-Based Biomarkers in Surgical Risk Stratification of First-Episode Primary Spontaneous Pneumothorax. [PDF]

Diagnostics (Basel)
Topaloglu O, Turut H, Senturk Topaloglu E, Gumus A, Sevilgen G.   +4 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

US Risk Evaluation and Mitigation Strategies with Elements to Assure Safe Use: A Longitudinal Analysis of REMS Modifications (2008-2022). [PDF]

Drug Saf
Morrato EH, Campagna EJ, LaCivita C, Toyserkani GA.   +3 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source