Results 181 to 190 of about 57,405 (292)

Navigating challenges in pediatric trial conduct: integrating bayesian sequential design with semiparametric elicitation for handling primary and secondary endpoints. [PDF]

BMC Med Res Methodol
Azzolina D, Baldi I, Bressan S, Khan MR, Dalt LD, Gregori D, Berchialla P.   +6 more
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

The Developmental Origins of Joint Attention: Infants' Early Joint Attention Bids. [PDF]

Infancy
Salter G, Carpenter M.
europepmc   +1 more source

Molecular Design of Highly Efficient Heavy‐Atom‐Free Near‐Infrared Cyanine Photosensitizers for Fluorescence Image‐Guided Photodynamic Therapy of Solid Tumors

Advanced Healthcare Materials, EarlyView.
Highly efficient heavy‐atom‐free NIR photosensitizers based on a heptamethine cyanine platform were developed for image‐guided photodynamic therapy. Both in vitro and in vivo results revealed that the R820‐3 photosensitizer with a highly twisted molecular structure exhibited potential for NIR fluorescence image‐guided photodynamic cancer therapy ...
Van‐Nghia Nguyen, Huixian Liang, Hyunsun Jeong, Jieun Bang, Chang Woo Koh, Kunemadihali Mathada Kotraiah Swamy, Sungnam Park, JaeHong Park, Fabiao Yu, Juyoung Yoon   +9 more
wiley   +1 more source

Proposed framework for medication delivery system in the Jordanian public health sector. [PDF]

BMC Med Inform Decis Mak
Elshebli A, Sweis G, Sharaf A, Jaghbeer GA.   +3 more
europepmc   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Special Issue "Molecular Mechanisms and Treatment of Allergic Reactions". [PDF]

Int J Mol Sci
Hopkins G, Fairclough LC.
europepmc   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Impact of storage conditions on the stability and biological efficacy of trans-arachidin-1 and trans-arachidin-3. [PDF]

PLoS One
Khongrungjarat P, Tothong C, Pankaew C, Phimsen S, Khamto N, Kijchalao N, Wongkham W, Wongkham P, Chuaymaung W, Thonnondang A, Limmongkon A.   +10 more
europepmc   +1 more source

MyPal user requirements elicitation

Report documenting in detail the user requirements of MyPal posing comprehensive requirements to WP3, WP4 and WP5.
openaire   +1 more source