Results 41 to 50 of about 141,708 (254)
Medical Image Anal., 2020 The recent global outbreak and spread of coronavirus disease (COVID-19) makes it an imperative to develop accurate and efficient diagnostic tools for the disease as medical resources are getting increasingly constrained.
Kai Gao +11 more
semanticscholar +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Frontiers in MicrobiologyBackground The unavoidable propagation of the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has underscored the urgent requirement for efficacious therapeutic agents.
C. Wang +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The mechanism design literature assumes too much common knowledge of the environment among the players and planner. We relax this assumption by studying implementation on richer type spaces. We ask when ex post implementation is equivalent to interim (or
Dirk Bergemann, Stephen Morris
core
Addressing the double burden of malnutrition in Egypt: do conditional cash transfers have a role? [PDF]
, 2009 Many developing countries are undergoing rapid socio-economic changes that impact on health and its social distribution. These changes can occur so rapidly that there is a resulting co-existence of diseases of affluence and diseases of poverty.
Aitsi-Selmi, A. +3 more
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Technology requirements for future Earth-to-geosynchronous orbit transportation systems. Volume 1: Executive summary [PDF]
Technologies including accelerated technology that are critical to performance and/or provide cost advantages for future space transportation systems are identified. Mission models are scoped and include priority missions, and cargo missions.
Caluori, V. A. +2 more
core +1 more source
Dual solutions for three-dimensional magnetohydrodynamic nanofluid flow with entropy generation
Journal of Computational Design and Engineering, 2019 This paper presents a formulation for simulating magnetohydrodynamic three-dimensional convective flow and heat transfer in a nanofluid by incorporating the complete viscous dissipation function in the energy equation.
H. Mondal, Mohammed Almakki, P. Sibanda
semanticscholar +1 more source