Results 111 to 120 of about 8,771,115 (304)
REQUIREMENT VALIDATION VS. REQUIREMENT ELICITATION
To support the evocation and validation of the goals achieved by the existing system and to illustrate problems of the old system, we suggest to capture current system usage using rich media (e.g., video, speech, pictures, etc.) and to interrelate those observations with the goal definitions .Therefore it becomes necessary to relate the parts of the ...
DHIRENDRA PANDEY +2 more
openaire +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Mobile Application for Thai & Foreign Tourists Visiting Thai Temple
This research gathered requirements from Thai and foreign tourists to successfully design Thai and English Android and IOS versions of a mobile application to provide an enhanced experience for tourists visiting the Phra Mahathat Woramahawihan (PMW ...
Kewalin Angkananon +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Change Impact Analysis based on Formalization of Trace Relations for Requirements [PDF]
Evolving customer needs is one of the driving factors in software development. There is a need to analyze the impact of requirement changes in order to determine possible conflicts and design alternatives influenced by these changes.
Berg, K.G. van den +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
EOSDIS/DADS requirements [PDF]
A brief summary of the Earth Observing System Data and Information System (EOSDIS) Core System (ECS) Data Archive and Distribution System (DADS) requirements is given.
Berbert, John, Kobler, Ben
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

