Results 51 to 60 of about 29,604,152 (395)

Requirements Analysis of a Quad-Redundant Flight Control System

open access: yes, 2015
In this paper we detail our effort to formalize and prove requirements for the Quad-redundant Flight Control System (QFCS) within NASA's Transport Class Model (TCM).
Backes, John   +3 more
core   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

An Analysis of the Features of Requirements Engineering Tools

open access: yesSystems, 2023
Many requirements engineering tools have been developed for gathering, documenting, and tracing requirements that can even be further processed for such purposes as analysis and transformation.
Mert Ozkaya   +2 more
doaj   +1 more source

An analysis of the requirements traceability problem [PDF]

open access: yes, 1994
In this paper1, we investigate and discuss the underlying nature of the requirements traceability problem. Our work is based on empirical studies, involving over 100 practitioners, and an evaluation of current support.
Finkelstein, A., Gotel, O.
core  

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

A Survey on Identifying and Addressing Business Analysis Problems

open access: yesFoundations of Computing and Decision Sciences, 2017
Despite the growing body of knowledge on requirements engineering and business analysis, these areas of software project are still considered problematic.
Jarzębowicz Aleksander, Marciniak Piotr
doaj   +1 more source

Computer-Aided Identification and Validation of Intervenability Requirements

open access: yesInformation, 2017
Privacy as a software quality is becoming more important these days and should not be underestimated during the development of software that processes personal data.
Rene Meis, Maritta Heisel
doaj   +1 more source

Blockchain for Supply Chain Traceability: Business Requirements and Critical Success Factors

open access: yesProduction and operations management, 2020
We seek to guide operations management (OM) research on the implementation of supply chain traceability systems by identifying business requirements and the factors critical to successful implementation.
Gabriella M. Hastig, M. Sodhi
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

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