Results 81 to 90 of about 29,604,152 (395)

Understanding business strategies of networked value constellations using goal- and value modeling [PDF]

, 2006
In goal-oriented requirements engineering (GORE), one usually proceeds from a goal analysis to a requirements specification, usually of IT systems. In contrast, we consider the use of GORE for the design of IT-enabled value constellations, which are ...
Gordijn, Jaap, Petit, Michael, Wieringa, Roel   +2 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Design and Analysis of Various Formwork Systems

International Journal of Innovative Science and Research Technology
Concrete is a fundamental material in the construction industry, with formwork playing a crucial role in shaping and strengthening concrete elements. It also represents a significant cost in building projects.
Haresh Sudhakarrao Bakale
semanticscholar   +1 more source

Model-Driven Engineering for Requirements Analysis [PDF]

11th IEEE International Enterprise Distributed Object Computing Conference (EDOC 2007), 2007
Requirements engineering (RE) encompasses a set of activities for eliciting, modelling, agreeing, communicating and validating requirements that precisely define the problem domain for a software system. Several tools and methods exist to perform each of these activities, but they mainly remain separate, making it difficult to capture the global ...
Baudry, Benoit, Nebut, Clémentine, Le Traon, Yves   +2 more
openaire   +5 more sources

Using protocol analysis to explore the creative requirements engineering process

, 2006
Protocol analysis is an empirical method applied by researchers in cognitive psychology and behavioural analysis. Protocol analysis can be used to collect, document and analyse thought processes by an individual problem solver.
Nguyen, Lemai, Shanks, Graeme
core   +2 more sources

A Requirements-based Framework for the Analysis of Socio-technical System Behaviour [PDF]

, 2003
Requirements Engineering's theoretical and practical developments typically look forward to the future (i.e. a system to be built). Under certain conditions, however, they can also be used for the analysis of problems related to actual systems in ...
Hall, Jon, Silva, Andrés
core   +2 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

NASA gateway requirements analysis [PDF]

NASA devotes approximately 40 percent of its budget to R&D. Twelve NASA Research Centers and their contractors conduct this R&D, which ranges across many disciplines and is fueled by information about previous endeavors. Locating the right information is
Doby, John S., Duncan, Denise R., Shockley, Cynthia W.   +2 more
core   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source