Results 231 to 240 of about 3,794,962 (338)

Rethinking Extracellular Vesicle Signaling

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Light‐Controlled Exposure of Cancer Cells to Reactive Oxygen Species Using Organic Semiconductor Thin Films

open access: yesAdvanced Materials Interfaces, EarlyView.
Spin‐coated films of the conjugated polymer F8T2 (poly (9,9‐dioctylfluorene‐alt‐bithiophene)) generate superoxide at the film‐medium interface, enabling precise delivery of reactive oxygen species (ROS) as visible‐light “ROS patches.” Coated surfaces drive rapid, localised cytotoxicity in MCF7 cancer monolayers under white light, providing a reagent ...
Joe Kaye   +8 more
wiley   +1 more source

Commodity risk assessment of <i>Hamamelis mollis</i> plants from the UK. [PDF]

open access: yesEFSA J
EFSA Panel on Plant Health (PLH)   +33 more
europepmc   +1 more source

Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection

open access: yesAdvanced Materials Interfaces, EarlyView.
This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon   +2 more
wiley   +1 more source

Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture

open access: yesAdvanced Materials Technologies, EarlyView.
The highly porous microelectrodes have been designed and printed on culture membranes, allowing to record electrophysiological neural activity for rodent brain slices. To keep the biocompatible nanoporous structure, the microelectrodes and insulative layer are fabricated on the bottom of culture membranes with only small connector pads added on the top.
Petro Lutsyk   +3 more
wiley   +1 more source

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