resaCPE: a rapid, low-cost colorimetric assay for the detection of carbapenemase-producing Enterobacterales. [PDF]
Jeffs MA +5 more
europepmc +1 more source
This study developed an injectable hydrogel (PGBP) based on polyglutamic acid. When loaded with amikacin (Ami@PGBP), the hydrogel system exhibits sustained drug release and potent antibacterial activity. It also reduces inflammation, effectively accelerating the closure and regeneration of infected wounds in vivo while demonstrating good biosafety ...
Yipeng Sun +9 more
wiley +1 more source
A Novel Method to Monitor the Evolution of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> Biofilms. [PDF]
Anguita R +3 more
europepmc +1 more source
Human Endothelium-on-a-Chip: Development of a Microfluidic Model for Cell Viability Assessment Under Oxidative Injury. [PDF]
Kirbus K +4 more
europepmc +1 more source
Kineochelins—A New Group of Siderophores From an Antarctic Bacterium
Genome‐guided analysis of an Antarctic Actinokineospora strain led to the discovery of kineochelins, a new group of siderophores involved in iron sequestration and microbial competition. Kineochelin production inhibits co‐occurring bacteria and clinically relevant yeasts, highlighting Antarctic microorganisms as promising sources of bioactive natural ...
Stanislava Kralova +12 more
wiley +1 more source
Energy Stress‐Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons
Energy stress via glucose deprivation activates AMPK and protects dopaminergic neurons from ferroptosis by limiting lipid peroxidation. In contrast, glucose availability supports ferroptosis through oxidizable lipid pools. ABSTRACT Ferroptosis, an iron‐dependent form of regulated necrosis, is implicated in the pathogenesis of Parkinson's disease (PD ...
Aurélie Jonneaux +8 more
wiley +1 more source
Growth factors-infused cellulose scaffolds support cost-efficient proliferation and differentiation of bovine stem cells for cultivated meat. [PDF]
Gershkoviz A +9 more
europepmc +1 more source
Reviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler—CPM‐HA20G
ABSTRACT Background Dermal fillers composed of hyaluronic acid (HA) combined with glycerol have been clinically shown to enhance skin hydration and quality; the precise mechanisms underlying their efficacy have yet to be fully elucidated. Aims Investigation of the dual hydration mechanisms, cell protection and tolerability, and tissue compatibility of ...
Kay Marquardt +9 more
wiley +1 more source
Conocarpan and Eupomatenoid-6 as Natural Prototypes for Antituberculosis Compounds. [PDF]
Silva LL +8 more
europepmc +1 more source
Inducing TRIB2-targeted protein degradation to reverse chemoresistance in acute myeloid leukaemia. [PDF]
Rigby E +13 more
europepmc +1 more source

