Results 51 to 60 of about 20,197 (313)

Osadnictwo wczesnośredniowieczne nad Jeziorem Wojnowickim [PDF]

, 2018
The article aims to present the results of rescue excavations of Early Medieval sites located in the area of the planned reservoir „Wonieść” (Great Poland) and carried out in the years 1976–1980.
Jankowska, Dobrochna
core   +2 more sources

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

Advanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu, Lan Pang, Wenqi Shi, Ting Feng, Zhi Dong, Yifeng Sheng, Sicong Zhou, Longtao Yu, Hao Guo, Ying Wang, Jiani Chen, Jianhua Huang   +11 more
wiley   +1 more source

Preliminary report on the excavation of the site Tiszakürt-Zsilke-tanya

Dissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2019
Colleagues of the Institute of Archaeological Sciences of the Eötvös Loránd University performed a rescue excavation at the site of Tiszakürt-Zsilke-tanya in 2018, within the series of excavations preceding the construction of the M44 motorway. Neolithic,
Kristóf Fülöp, Denisa M. Lönhardt, Nóra Szabó, Gábor Váczi   +3 more
doaj   +1 more source

50 Years of Archaeology in the University of Łódź - Summary [PDF]

, 1995
Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej ...
Kajzer, Leszek
core  

Excavation at Aguas Buenas, Robinson Crusoe Island, Chile, of a gunpowder magazine and the supposed campsite of Alexander Selkirk, together with an account of early navigational dividers [PDF]

, 2007
Excavations were undertaken of a ruined building at Aguas Buenas, identified as an 18th-century Spanish gunpowder magazine. Evidence was also found for the campsite of an early European occupant of the island.
Anderson R.G.W., Babcock B.E, Bardelli A, Bardelli A, Baudet D., Bennett J.A, Craddock P.T., Eremin K., Holbrook M., Mortimer C, Prado C, Reyes V., Stuiver M., Talma A.S., Taylor E.G.R., Thomas F.W.L, Van Poelje O, Vicuña Mackenna B   +17 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Repatriation, doxa, and contested heritages: the return of the Altai princess in an international perspective [PDF]

, 2014
Using Pierre Bourdieu's concepts of habitus and doxa, the authors analyze the contested heritage debates surrounding the sensational Scythian burial discovery of the Altai Princess, also called the Ice Maiden, on the Ukok plateau.
Plets, Gertjan, Konstantinov, Nikita, Soenov, Vasilii, Robinson, Erick   +3 more
core  

An Iona of the East : the early-medieval monastery at Portmahomack, Tarbat Ness [PDF]

, 2004
A new research programme located on the Tarbat peninsula in north-east Scotland offers the first large-scale exposure of a monastery in the land of the Picts.
Carver, Martin
core   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source