Results 51 to 60 of about 285,597 (291)

Site and Artefact data from Excavations at Roxwell Quarry, Essex 1997-2000

open access: yes, 2021
This collection comprises reports, finds data, a site drawing and images from excavations at Roxwell Quarry. Archaeological rescue excavations were carried out from 1997 to 2000 in advance of mineral extraction and revealed multiphase landscape remains ...
Mark Germany
core   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

open access: yesAdvanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao   +5 more
wiley   +1 more source

Location awareness in a mountain rescue domain [PDF]

open access: yes, 2007
The notion of location awareness in a Mountain Rescue domain is critical for the mission coordinator of a Mountain Rescue Team who tries to organize the team and make informed decisions for all its members. The knowledge of location of each member of the
Georgopoulos, Panagiotis
core   +4 more sources

Preliminary report on the excavation of the site Tiszakürt-Zsilke-tanya

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2019
Colleagues of the Institute of Archaeological Sciences of the Eötvös Loránd University performed a rescue excavation at the site of Tiszakürt-Zsilke-tanya in 2018, within the series of excavations preceding the construction of the M44 motorway. Neolithic,
Kristóf Fülöp   +3 more
doaj   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

open access: yesAdvanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao   +10 more
wiley   +1 more source

Competing in the RoboCup Rescue Robot League [PDF]

open access: yes, 2010
RoboCup Rescue is an international competition in which robots compete to find disaster victims in a simulated earthquake environment. It features both a Rescue Simulation League (RSL) which is entirely computer simulated, and a Rescue Robot League (RRL)
Tandy, Michael J.   +2 more
core  

Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures

open access: yesAdvanced Science, EarlyView.
ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels   +12 more
wiley   +1 more source

Field fortifications from the Second World War: possibilities of archaeological research on post-military landscapes in South Moravia (Czech Republic)

open access: yesActa Universitatis Carolinae Geographica, 2019
Field fortifications from the end of World War 2 which were located in South Moravia are almost forgotten nowadays. This paper presents first results of archaeological research of their remains.
Jiří Zubalík
doaj   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

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