Results 61 to 70 of about 322,552 (311)
RESPECT: A personal development programme for young people at risk of social exclusion [PDF]
, 2007 This project report discusses the development and delivery of the RESPECT project, a personal development programme run by Cheshire Fire and Rescue Service for young people in Cheshire who are at risk of social ...
Collier, Kevan +2 more
core
, 2023 Bakalářská práce se zabývá prací Skalní záchranné služby z. s. V teoretické části je detailně popsána metodika a náplň práce skalních záchranářů. Zvýšená pozornost je věnována metodice záchranné akce ve skalách, vybavení záchranářů Skalní služby a ...
Volf, Petr
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The Journal of Qazvin University of Medical Sciences, 2017 Background: Work-related musculoskeletal disorders, is the cause of most disability and absences created to work. Objective: This study was done in order to survey of effective occupation risk factors on absence from work and going to the doctor caused ...
P. Heydari, S. Varmazyar, Ch. Hakimi
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
, 2016 An architecture suitable for the control of multiple unmanned aerial vehicles deployed in Search & Rescue missions is presented in this paper. In the proposed system, a single colocated human operator is able to coordinate the actions of a set of robots ...
J. Cacace +17 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Decentralised Coordination in RoboCup Rescue
, 2010 Emergency responders are faced with a number of significant challenges when managing major disasters. First, the number of rescue tasks posed is usually larger than the number of responders (or agents) and the resources available to them.
Ramchurn, S +13 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source