Results 281 to 290 of about 66,967,971 (330)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

"How can we talk about our struggles?" reflections on researcher wellbeing and recommendations for psychosocial support for researchers in conflict-affected areas. [PDF]

Confl Health
Jeffery L, Lowe L, Falisse JB, Ghafoerkhan R.   +3 more
europepmc   +1 more source

A conversation with Kevin Gibbs, MD, associate professor, Wake Forest University School of Medicine

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

2002 election campaign: summing up [PDF]

, 2002
Research, Update
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Grant Funding for Immigrant Cardiovascular Health Research in the US and Canada.

JAMA Netw Open
Bedrouni W, Bedrouni M, Fahed AC, Anand SS, Bessissow A, Touyz R, Huynh T.   +6 more
europepmc   +1 more source

'Manifesto of the communist party':1997 [PDF]

, 1998
Research, Update
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Scholarship of teaching and learning of nursing faculty members: a protocol for a scoping review. [PDF]

BMJ Open
Heidarzadeh H, Seyedfatemi N, Peyrovi H, Zareiyan A, Mirhosseini F.   +4 more
europepmc   +1 more source