Results 21 to 30 of about 33,710,537 (347)
Questo numero di IUL Research esplora il complesso panorama della valutazione nella scuola primaria, un tema cogente nell’attuale scenario della formazione del primo ciclo in Italia. La valutazione accompagna tutti i momenti della didattica, supportando
IUL Research
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Despite the many thousands of research studies published every year, evidence for making clinical decisions is often lacking. The main problem is that the evidence available is generated in conditions very different from those that prevail in routine ...
BOLDER Research Group
doaj +1 more source
A Conceptual Model of Service Quality and Its Implications for Future Research
The attainment of quality in products and services has become a pivotal concern of the 1980s. While quality in tangible goods has been described and measured by marketers, quality in services is largely undefined and unresearched.
A. Parasuraman, V. Zeithaml, L. Berry
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
La globalizzazione e la post-globalizzazione richiedono una nuova riflessione sulla diversità culturale e sulle dinamiche interculturali nei contesti contemporanei. Le autobiografie linguistiche di parlanti bilingui e plurilingui offrono una prospettiva
IUL Research
doaj +1 more source
Researcher–researched relationship in qualitative research: Shifts in positions and researcher vulnerability [PDF]
The researcher role is highly debated in qualitative research. This article concerns the researcher-researched relationship.A group of health science researchers anchored in various qualitative research traditions gathered in reflective group discussions over a period of two years.Efforts to establish an anti-authoritarian relationship between ...
Råheim, Målfrid+5 more
openaire +8 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source