Results 61 to 70 of about 66,967,971 (330)

The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice

open access: yesFEBS Letters, EarlyView.
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Ranking U-Sapiens Colombia-2010_2

open access: yesBoletín Científico Sapiens Research, 2011
Los principales objetivos de esta investigación son los siguientes: (1) que la comunidad científica nacional e internacional y la sociedad en general conozcan los resultados del Ranking U-Sapiens Colombia 2010_2, el cual clasifica a cada institución de ...
Sapiens Research Group
doaj  

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Ranking U-Sapiens 2013-1

open access: yesBoletín Científico Sapiens Research, 2014
Objetivos: (1) Publicar el listado de universidades certificadas por Sapiens Research Group; (2) el séptimo reporte de las mejores instituciones de educación superior colombianas según indicadores de investigación; (3) el listado de las 10 IES que más ...
Sapiens Research Group
doaj  

Corporate governance and institutions—A review and research agenda [PDF]

open access: bronze, 2020
Alessandro Zattoni   +3 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Home - About - Disclaimer - Privacy