Results 101 to 110 of about 74,584,174 (296)

Queensland Emergency Medicine Research Foundation: special report

open access: yes, 2011
Development of any new profession is dependent on the development of a special body of knowledge that is the domain of the profession. Key to this is research.
Gerry FitzGerald   +7 more
core   +1 more source

A bibliometric analysis of research productivity of emergency medicine researchers in South Korea [PDF]

open access: yes, 2017
OBJECTIVE: During the past 20 years, over 1,400 doctors have been certified as emergency physicians in Korea. The number of scientific publications in the field of emergency medicine has also increased.
주영선   +5 more
core   +1 more source

Human macrophage pro‐inflammatory polarization in response to free cholesterol and cholesterol remnants

open access: yesPhysiological Reports
Atherosclerosis is a chronic inflammatory disease of the blood vessels caused by elevated levels of lipoproteins. The hyperlipoproteinemia triggers a series of cellular changes, particularly the activation of the macrophages, which play a crucial role in
Karel Paukner   +8 more
doaj   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Potential mechanisms of acupuncture treatment for rheumatoid arthritis: a study based on network topology and machine learning

open access: yesChinese Medicine
Background Rheumatoid arthritis (RA) is a systemic autoimmune disease that requires multitarget therapeutic strategies. Acupuncture, an integrative therapy of traditional Chinese medicine (TCM), has shown efficacy in the clinical treatment of RA, but its
Feiyang Li   +12 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hypoxia Regulates MicroRNA Expression in the Human Carotid Body

open access: yes, 2017
10.1007/978-3-319-91137-3_3Advances in Experimental Medicine and Biology107125 ...
Poelllinger L.   +22 more
core   +1 more source

Brown adipose tissue: a potential therapeutic target for preventing cardiovascular disease in metabolic disorders

open access: yesDiabetology & Metabolic Syndrome
Background Obesity and Type 2 diabetes (T2D) remain significant health challenges contributing to cardiovascular complications. This study aimed to investigate brown adipose tissue (BAT) and connexin43 (Cx43) in obese T2D rats and evaluate the effects of
Tamara Egan Beňová   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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