Results 101 to 110 of about 59,223,825 (281)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The essence and pedagogical basis of the digital eco-system formation for activating research and innovation activities of undergraduates

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки
Importance. Currently, there is a need for the use of modern digital technologies to accompany the educational process of training young researchers focused on the generation of new ideas, technology transfer.
M. S. Chvanova, I. A. Kiseleva
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

METHODOLOGICAL AND METHODICAL FOUNDATIONS EVALUATION OF EFFECTIVENESS OF INVESTMENT PROJECTS IN SCIENTIFIC RESEARCH

open access: yesВестник университета, 2019
The authors substantiate the features of investment projects in research and development; Explore methodological approaches to assessing the effectiveness of investment projects that have evolved in modern domestic and foreign economic science ...
G. Ryazanova, A. Sazanova
doaj  

Assessment of future physics teacher’s readiness to develop pupils’ research abilities: diagnostic toolkit

open access: yesFrontiers in Education
The relevance of the research topic is the problem of preparing future physics teachers of Kazakhstan to organize research activities of schoolchildren. The work is aimed at considering the problem of finding approaches to assessing the level of teachers’
Ainur Seitkhanova   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An exploration of demand for physical activity [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The aim of this thesis is to contribute to the understanding of demand for physical activity.
Anokye, Nana Kwame
core   +3 more sources

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