Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A comprehensive categorical and bibliometric analysis of published research articles on pediatric pain from 1975 to 2010 [PDF]
The field of pediatric pain research began in the mid-1970s and has undergone significant growth and development in recent years as evidenced by the variety of books, conferences, and journals on the topic and also the number of disciplines engaged in ...
Dol, Justine +16 more
core +1 more source
Evaluation of the effects produced by triggering pyrotechnic articles for automotive use by exposure to various hazardous external stimuli [PDF]
The object of the evaluation of the risk factors that may lead to the accidental initiation of the semi-finished products containing pyrotechnic articles in the process of handling / use / storage / transport is represented by the estimation and ...
Garaliu-Bușoi Bogdan +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Death of Review Articles in Humanities: A Case study on World LIS Journals [PDF]
This study reveals the current status of articles published in Library and Information Science (LIS) journals. Using the citation site “Scopus”, the number of published articles in 32 LIS journals were extracted, illustrated, and analyzed ...
khosrowjerdi, mahmood
core
Potential factors influencing the rhetorical patterns of research article discussion sections
The present study reports potential factors influencing the rhetorical patterns of research articles (RA) discussion sections. The study was conducted by utilizing descriptive qualitative research.
Lulus Irawati
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Editorial Board: Professor Ülo Niinemets (Estonian Universtiy of Life Sciences), Professor Erkki Karo (Tallinn Technical University, TalTec), Professor Rainer Kattel (Tallinn Technical University, TalTec), Professor Richard Villems (Universtiy of Tartu ...
Estonian Research Council
core +1 more source
PPMP and Gini index among articles considered as research articles.
Distribution of the (A) PPMP author(s) and (B) the Gini index in relation to journal size, and (C) comparison between the PPMP and the Gini index, among articles considered as research articles (i.e., original article, case reports, and reviews ...
Clara Locher (805603) +5 more
core +1 more source
Full articles will be available online by 12 January 2015.
Editorial Office
doaj +1 more source

