Results 91 to 100 of about 9,915,672 (306)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Editorial: Linked open bibliographic data for real-time research assessment. [PDF]

open access: yesFront Res Metr Anal, 2023
Ben Aouicha M, Turki H, Hadj Taieb MA.
europepmc   +1 more source

Measuring back: bibliodiversity and the Journal Impact Factor™ brand, a case study of IF-journals included in the 2021 Journal Citations Report™

open access: yesInsights: The UKSG Journal
Little attention has been devoted to whether the impact factor (IF) can be considered a responsible metric in light of bibliodiversity. This article critically engages with this question in measuring the following variables of IF journals included in the
Marjorie Bardiau, Christophe Dony
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Design, Implementation, and Assessment of an Undergraduate Interdisciplinary Watershed Research Laboratory [PDF]

open access: yes, 2002
This article discusses the establishment of Shippensburg University's Burd Run Interdisciplinary Watershed Research Laboratory and the advantages of linking disciplinary perspectives across courses in geology, geography, biology, and teacher education ...
Christopher Woltemade, William Blewett
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

How did Estonia become the world’s fastest-growing country in scientific wealth? [PDF]

open access: yesProceedings of the Estonian Academy of Sciences
The concept of scientific wealth is defined as the average number of citations per paper published by scientists from a given country or territory over a fixed period.
Jüri Allik, Mart Saarma, Anu Realo
doaj   +1 more source

Spacecraft software training needs assessment research [PDF]

open access: yes
The problems were identified, along with their causes and potential solutions, that the management analysts were encountering in performing their jobs. It was concluded that sophisticated training applications would provide the most effective solution to
Golas, Katharine, Ratcliff, Shirley
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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