Results 211 to 220 of about 29,857,715 (400)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Editorial: Quality and quantity in research assessment: examining the merits of metrics, volume II. [PDF]

Front Res Metr Anal
Montazerian M, Shaghaei N, Drachen TM, Dorch BF.   +3 more
europepmc   +1 more source

Seismic Safety Margins Research Program (Phase I). Project I. Plant/site selection, plant/site selection assessment report

, 1979
Raymond L. Reed
openalex   +1 more source

The Cinderella of academia: Is higher education pedagogic research undervalued in UK research assessment?

, 2018
Debby R. E. Cotton, W. Miller, Pauline Kneale   +2 more
semanticscholar   +1 more source

Assessment News, Vol 2, Issue 1 [PDF]

, 2011
Office of Planning, Assessment and Institutional Research, Pace University
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Quantitative research assessment: using metrics against gamed metrics. [PDF]

Intern Emerg Med
Ioannidis JPA, Maniadis Z.
europepmc   +1 more source

Electric and Hybrid Vehicle System Research and Development Project: hybrid vehicle potential assessment. Volume V. Flywheel systems

, 1979
S. G. Liddle
openalex   +2 more sources

Common Data Set, 2002-2003 [PDF]

, 2002
Office of Institutional Research and Assessment, Bridgewater State College
core   +1 more source

A research review of quality assessment for software [PDF]

Measures were recommended to assess the quality of software submitted to the AdaNet program. The quality factors that are important to software reuse are explored and methods of evaluating those factors are discussed.

core   +1 more source