CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Electronic State Modulation Interfaced With Interfacial Electric Fields: Ca Site Activation Promoting Photocatalytic Hydrogen Evolution in CdS/Ca<sub>2</sub>Co<sub>2</sub>O<sub>5</sub> S-Scheme Heterojunction. [PDF]
Jin Z +6 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Microbial enzyme-driven carbon-nitrogen cycling processes of greenhouse gases in sandy sediments of river-oasis systems in arid regions. [PDF]
Lv G +8 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
NATIONAL INSTITUTE OF TRAUMATOLOGY AND ORTHOPEDICS: A BIBLIOMETRIC STUDY. [PDF]
Nascimento RFO +2 more
europepmc +1 more source
Developing Excellence in Participatory Research and Co-Production
This presentation explores participatory research and co-production in the field of autism studies. Barriers and opportunities for inclusive practice are examined with examples from a range of projects. In conclusion this presentation highlights the Participatory Autism Research Collective (PARC) which was initially set up with the purpose of bringing ...
openaire
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Powering Up: a qualitative evaluation of the art and science of meaningful co-production for health equity. [PDF]
Singh G, Salama M, Zhu H.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source

