Results 71 to 80 of about 59,054,444 (289)

The potential role of palygorskite and probiotics complex on the laying performance and faecal microbial community in Xuefeng black-bone chicken

open access: yesItalian Journal of Animal Science, 2022
This experiment was conducted to investigate the effects of palygorskite and probiotics complex (Pal–Pro) supplementation on laying performance, the microflora structure and biodiversity of Xuefeng black-bone chicken.
Yuying Deng   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hydrogen embrittlement susceptibility of the X70 pipeline steel substrate and weld in simulated coal gas containing hydrogen environment

open access: yes工程科学学报, 2017
The diffusion and accumulation behaviour of hydrogen in X70 pipeline steel were investigated via hydrogen permeation test, hydrogen diffusion simulation, and hydrogen content test technology in a simulated coal gas environment (4 MPa total pressure, 0.2 ...
GUAN Hong-peng   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The effect of dry cow winter management system on feed intake, performance and estimated energy demand

open access: yesAnimal, 2010
This research compared three wood-chip out-wintering pad (OWP; an unsheltered OWP; a sheltered OWP (both with a concrete feed apron); and an unsheltered OWP with silage provided directly on top of the wood-chip bedding (self-feed OWP)) designs and ...
K. O’Driscoll   +4 more
doaj   +1 more source

Co-production: What Makes Co-Production Work? Evidence from Pakistan [PDF]

open access: yes, 2016
Purpose  In developing countries there is a growing recognition that co-production offers more cost effective and responsive service delivery options in low income areas.
Farooqi, Seemab Ara   +1 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Beyond the horizon: new directions in research coproduction

open access: yesHealth Research Policy and Systems
Research coproduction is no longer a subordinate approach; it is reshaping how health research is conceived, conducted and applied. Integrated knowledge translation (IKT), the Canadian term for coproduction, champions researchers and knowledge users in ...
Anita Kothari   +2 more
doaj   +1 more source

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