Results 131 to 140 of about 1,746,775 (307)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Enhancing evidence-based practice into healthcare: Exploring the role of scientific skills in occupational therapists-

Scandinavian Journal of Occupational Therapy
Background Research utilization and evidence-based practice (EBP) in occupational therapy rely on essential scientific skills. Despite prior research exploring factors influencing EBP, a gap remains in understanding the specific scientific competencies ...
Desirée Valera-Gran, Irene Campos-Sánchez, Daniel Prieto-Botella, Paula Fernández-Pires, Miriam Hurtado-Pomares, Iris Juárez-Leal, Paula Peral-Gómez, Eva María Navarrete-Muñoz   +7 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Young Children’s cliques : a study on processes of peer acceptance and cliques aggregation [PDF]

, 2015
A considerable amount of research has examined the link between children’s peer acceptance, which refers to the degree of likability within the peer group, social functioning and emotional wellbeing, at a same age and in a long term perspective ...
Brighi, Antonella, Guarini, Annalisa, Mazzanti, Chiara, Sansavini, Alessandra   +3 more
core  

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

ICT AS A COMPONENT OF PREPARATION OF THE FUTURE ELEMENTARY SCHOOL TEACHERS TO CONDUCT EDUCATIONAL RESEARCH

Ìнформаційні технології в освіті, 2015
Article devoted to the mechanism of formation of research competence of future primary school teachers. Illuminated by a hierarchical system of assumptions implementing person-centered paradigm to improve research competencies of future teachers in ...
B. Andrievskiy, T. Vinnyk
doaj  

Service-learning @ Lingnan : facts & figures

, 2015
This booklet summarizes the results and findings from the ongoing research and evaluation studies of Service-Learning. It provides supporting evidence that Service-Learning enhances students’ development in seven learning outcomes: Subject-Related ...
Lingnan University, Office of Service-Learning, Lingnan University   +1 more
core  

Rangatahi Wahine: Overcoming the odds – preliminary results [PDF]

, 2003
The purpose of my research was to identify factors that have contributed to the development of resilience in young Māori girls’ lives. Incorporated into this was an exploration of their psychosocial competence makeup, to see whether their sense of ...
Merritt, Kiri
core   +1 more source