Results 241 to 250 of about 25,624,885 (337)

Privacy Protection for Open Sharing of Psychiatric and Behavioral Research Data: Ethical Considerations and Recommendations. [PDF]

Alpha Psychiatry
Zhang Y, Fan S, Hui H, Zhang N, Li J, Liao L, Ke C, Zhang D, Su S, Song Z, Zhang Y, Du Q, Liu L, Wang L, Yang L, Li J, Xu L, Xiao S, Shi L, Xiao X, Wang W, Sun N, He Q, Hao R, Wu J, Tian Z, Lou Y, Yao Q, Ming WK, Jiang F, Zhou X, Wang M, Sun X, Wu Y, Behavioral Epidemiology Education Working Commission of CMEA.   +34 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

An analysis of the effects of sharing research data, code, and preprints on citations. [PDF]

PLoS One
Colavizza G, Cadwallader L, LaFlamme M, Dozot G, Lecorney S, Rappo D, Hrynaszkiewicz I.   +6 more
europepmc   +1 more source

Ethical and methodological issues in data sharing between two research [PDF]

, 2004
Hanson, J
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Workshop @ deRSE19: Libraries for Research Software & Engineers

Library Ideas, 2019
Ronny Gey, Katrin Leinweber, Alexander Struck, Robert Strötgen, Christian Pietsch   +4 more
doaj   +1 more source

Adherence to research data sharing practice in dentistry over the last decade: a cross-sectional study. [PDF]

Rev Cient Odontol (Lima)
Oliveira AM, Barreto Moreno L, Dos Santos Fernandez M, Mustafa Gomes Muniz FW, Fernandes Montagner A.   +4 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The most prevalent perceived barriers to sharing research data at the point of manuscript acceptance in health and life sciences: a survey at the University of Bristol. [PDF]

F1000Res
Bajraktari R, Booth F, Munafo M, Beazley-Long N.   +3 more
europepmc   +1 more source