Results 151 to 160 of about 82,140,510 (321)
Huli yanjiu, 2017 Objective:To probe into the research status quo,research hotspots and research frontier of mobile health,so as to provide a theoretical basis for Chinese nurses carrying out mobile health related research and practice.Methods:Bibliometrics,coword ...
Chen Xuemei, Zhou Lanshu
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Assessing researchers with a focus on research integrity [PDF]
The Lancet, 2019 openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Annual Report (Focus on the Global South
, 2004 Focus on the Global South was established in 1995 to challenge neoliberalism, militarism and corporate-driven globalization while strengthening just and equitable alternatives. We work in solidarity with the Global South – the great majority of humanity
Focus on the Global South (Program)
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
HRB Strategic Business Plan 2010 – 2014: The future of Irish health research
, 2009 The new Health Research Board (HRB) strategic business 2010 – 2014 plan will focus on improving people’s health, transforming our health services and supporting new enterprise and the economy over the next five years. A shift in focus will see the HRB
Health Research Board
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
National Mental Health Research Strategy [PDF]
This first national mental health research strategy for Ireland presents a unique opportunity to create a thriving mental health research system that can support mental health and wellbeing for all.
Health Research Board
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