Results 41 to 50 of about 144,729 (260)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Advancing timber construction: historical growth, research frontiers, and time series forecasting

open access: yesJournal of Asian Architecture and Building Engineering
Lauded for its capacity to curtail building energy consumption and enhance environmental performance compared to traditional mineral-based materials, wood has gained substantial traction in the construction sector.
Harrison Huang, Shan Su, Lu Li
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Prokaryotic ribosomal RNA stimulates zebrafish embryonic innate immune system

open access: yesBMC Research Notes, 2020
Objectives Cell-culture studies reported that prokaryotic RNA molecules among the various microbe-associated molecular patterns (MAMPs) were uniquely present in live bacteria and were categorized as viability-associated MAMPs.
Abhishikta Basu   +3 more
doaj   +1 more source

Psychoneuroimmunology: The new frontier in suicide research

open access: yesBrain, Behavior, & Immunity - Health, 2021
Elucidating complex, multifactorial phenomena like suicide and suicidal behaviors (SSB) require multidisciplinary fields such as Psychoneuroimmunology (PNI).
Sudan Prasad Neupane
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Visualization analysis of paper research of clinical nursing funds

open access: yesHuli yanjiu, 2017
To know about the status quo of the authors,organizations of clinical nursing fund,research focus and frontier and to provide references for the future development of clinical nursing research.
谭茜, 程金莲, 李玉姣
doaj  

Remote Sensing-Based Advances in Climate Change Impacts on Agricultural Ecosystem Respiration

open access: yesAgriculture
Global climate change is exerting a growing impact on agricultural ecosystems. Accurately assessing the spatiotemporal dynamics of agricultural ecosystem respiration and its response mechanisms to climate has therefore emerged as a critical issue in ...
Xingshuai Mei   +5 more
doaj   +1 more source

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