The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Jahn-Teller Distortions in Pseudo-Octahedral Low-Spin Ni(III) Complexes With O,O or N,N Bidentate Ligands: A DFT Study. [PDF]
Conradie J.
europepmc +1 more source
Performance of large language models (GPT-5.2, Gemini 3 Pro, Claude Sonnet 4.6 and Grok 4.1) on the Fellowship of The Royal College of Surgeons Urology Part A examination. [PDF]
Kafagi AR, Atassi N, Kafagi AH.
europepmc +1 more source
Low-altitude economy: next frontier in spatial exploration and economic development. [PDF]
Shum HY, Li S.
europepmc +1 more source
COPD in Africa in the Post-COVID Era: A GBD 2023 Analysis of Trends, Demographic Drivers and Health-System Performance. [PDF]
Shi B, Liu J, Zhou F, Han B, Wang Y.
europepmc +1 more source
Global, regional, and national burdens of human papillomavirus-associated cervical cancer attributable to sexually acquired human papillomavirus infections among individuals aged 10-54 years from 1990 to 2021: findings from the Global Burden of Disease study 2021. [PDF]
Nov P +8 more
europepmc +1 more source
A concept for inferring ‘frontier research’ in grant proposals
International audienceThis paper discusses a concept for inferring attributes of 'frontier research' in peer-reviewed research proposals under the popular scheme of the European Research Council (ERC).
Marianne Hörlesberger +2 more
exaly +2 more sources

