Results 41 to 50 of about 50,327,648 (262)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Prokaryotic ribosomal RNA stimulates zebrafish embryonic innate immune system

open access: yesBMC Research Notes, 2020
Objectives Cell-culture studies reported that prokaryotic RNA molecules among the various microbe-associated molecular patterns (MAMPs) were uniquely present in live bacteria and were categorized as viability-associated MAMPs.
Abhishikta Basu   +3 more
doaj   +1 more source

Psychoneuroimmunology: The new frontier in suicide research

open access: yesBrain, Behavior, & Immunity - Health, 2021
Elucidating complex, multifactorial phenomena like suicide and suicidal behaviors (SSB) require multidisciplinary fields such as Psychoneuroimmunology (PNI).
Sudan Prasad Neupane
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

Visualization analysis of paper research of clinical nursing funds

open access: yesHuli yanjiu, 2017
To know about the status quo of the authors,organizations of clinical nursing fund,research focus and frontier and to provide references for the future development of clinical nursing research.
谭茜, 程金莲, 李玉姣
doaj  

Remote Sensing-Based Advances in Climate Change Impacts on Agricultural Ecosystem Respiration

open access: yesAgriculture
Global climate change is exerting a growing impact on agricultural ecosystems. Accurately assessing the spatiotemporal dynamics of agricultural ecosystem respiration and its response mechanisms to climate has therefore emerged as a critical issue in ...
Xingshuai Mei   +5 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

A Bibliometric Analysis of the Outdoor Thermal Environment Based on CiteSpace

open access: yesBuildings
The outdoor thermal environment (OTE) is closely related to sustainable urban development and human living, and related research has attracted widespread attention.
Chao Xie, Tangjun Feng, Li Hu
doaj   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

open access: yesAdvanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares   +3 more
wiley   +1 more source

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