Results 21 to 30 of about 50,326,394 (261)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Diversity and compositional differences of the airborne microbiome in a biophilic indoor environment

Scientific Reports, 2023
Biophilic design based on indoor planting plays an important role in human physical and mental well-being. To investigate and assess the effects of indoor planting on air quality, we sequenced 16S rRNA gene amplicons to compare the airborne bacterial ...
Akinobu Toyoda, Yusuke Shibata, Yuzy Matsuo, Kumi Terada, Hiroki Sugimoto, Koichi Higashi, Hiroshi Mori, Akinori Ikeuchi, Masakazu Ito, Ken Kurokawa, Satoshi Katahira   +10 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Vicissitudes and prospects of green roof research: a two-decade systematic bibliometric review

Frontiers in Ecology and Evolution
Urban green roofs have emerged as an innovative nature-based solution for enhancing urban sustainability and resilience. Based on the Web of Science Core Collection database, the scholarly papers on green roofs published in the past two decades were ...
Chunping Xie, Dawei Liu, C. Y. Jim
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Development of Human Support Robot as the research platform of a domestic mobile manipulator

ROBOMECH Journal, 2019
There has been an increasing interest in mobile manipulators that are capable of performing physical work in living spaces worldwide, corresponding to an aging population with declining birth rates with the expectation of improving quality of life (QoL).
Takashi Yamamoto, Koji Terada, Akiyoshi Ochiai, Fuminori Saito, Yoshiaki Asahara, Kazuto Murase   +5 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Frontier Research on Low-Resource Speech Recognition Technology

Sensors, 2023
With the development of continuous speech recognition technology, users have put forward higher requirements in terms of speech recognition accuracy. Low-resource speech recognition, as a typical speech recognition technology under restricted conditions,
Wushour Slam, Yanan Li, Nurmamet Urouvas
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Advancing timber construction: historical growth, research frontiers, and time series forecasting

Journal of Asian Architecture and Building Engineering
Lauded for its capacity to curtail building energy consumption and enhance environmental performance compared to traditional mineral-based materials, wood has gained substantial traction in the construction sector.
Harrison Huang, Shan Su, Lu Li
doaj   +1 more source