Results 141 to 150 of about 4,809,627 (260)

Navigating Scientific Inquiry in East Africa Amidst Declining Research Funding. [PDF]

East Afr Health Res J
Wandiga S, Ntakarutimana L, Mashauri F, Twungubumwe N.   +3 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

How to integrate patient and carer perspectives, methodological rigor, and ethics into biomedical research funding. [PDF]

PLoS Biol
Lichtenberg H, Müller C, Lindeman H, Ali L, Minheere A, van den Eijnden M, Dirnagl U.   +6 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Fall research funding in the US from 2018-2022 relative to fall-related mortality, disability-adjusted life years, and healthcare expenditures. [PDF]

Am J Health Promot
Samih MS, Krauss MJ, Stark SL.
europepmc   +1 more source

Comparison of Inpatient and Emergency Department Costs to Research Funding for Functional Neurologic Disorder: An Economic Analysis. [PDF]

Neurology
Stephen CD, Fung V, Perez DL, Espay AJ.
europepmc   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Advancing global equity in liver disease research funding: the case of metabolic dysfunction-associated and alcohol-associated liver disease. [PDF]

BMJ Open Gastroenterol
Huynh DJ, Obusan M, Lu J, Albhaisi O, Albhaisi S.   +4 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Incidence, Mortality, and Federal Research Funding by Cancer Type in the US.

JAMA Netw Open
Mohindroo C, Thomas A.
europepmc   +1 more source