Results 201 to 210 of about 4,809,627 (260)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Assessing the potential of a Bayesian ranking as an alternative to consensus meetings for decision making in research funding: A case study of Marie Skłodowska-Curie actions. [PDF]

PLoS One
Heyard R, Pina DG, Buljan I, Marušić A.   +3 more
europepmc   +1 more source

Patient engagement in a Canadian health research funding institute: implementation and impact. [PDF]

BMJ Open
Richards DP, Twomey R, Flynn T, Hunter L, Lui E, Stordy A, Thomas C, Khan K.   +7 more
europepmc   +1 more source

Challenges to ethical public engagement in research funding: a perspective from practice. [PDF]

Open Res Eur
Giannelos K, Wiarda M, Doorn N.
europepmc   +1 more source

The landscape of biomedical research funding in Brazil: a current overview. [PDF]

Int Braz J Urol
Gomes CM, Marchini G, de Bessa J, Carvalhal G, Caldeira MPR, Saldiva PH, Krieger JE, Agena F, Reis S, Paschoal C, Froes M, Srougi M, Nahas WC, Favorito LA.   +13 more
europepmc   +1 more source

Incorporating community perspective in research funding: creation of the National Multiple Sclerosis Society Community Review of MS Research Committee. [PDF]

Res Involv Engagem
Lampe AT, Zackowski KM.
europepmc   +1 more source