Results 141 to 150 of about 3,895,024 (310)

Review: Ardra L. Cole & J. Gary Knowles (Eds.) (2001). Lives in Context: The Art of Life History Research

open access: yesForum: Qualitative Social Research, 2004
COLE and KNOWLES present a book that is simultaneously an introduction to the field, an edited collection of mainly Canadian examples of research issues emerging from the field and a manifesto for arts-informed research.
Volker Wedekind
doaj  

International Federation for Research in Women’s History 2024 Conference

open access: yes
Margaret Allen, Ana Stevenson and Michelle Staff share their experiences of attending the 2024 International Federation for Research in Women’s History ...
Allen, Margaret   +2 more
core  

United States Army in the World War, 1917-1919: bulletins, GHQ, AEF, volume 17.

open access: yes, 2011
To encourage further research in the history of World War I and to fill a gap in the Army's historical documentation of that conflict, the Center of Military History has created a World War I series of publications consisting of new monographs and ...
Center of Military History
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

WS10: British Contributions to Medical Research and Education in Africa after the Second World War (03-Jun-1999)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “British Contributions to Medicine in Africa after the Second World War” held by the History of Twentieth Century Medicine Group, 03-Jun-1999.

core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Scottish environmental history and the (mis)use of Soums

open access: yes, 2006
For much of the historical period pasture was apportioned into relatively small units across much of Europe. Scotland was no exception to this norm and here such units were called soums.
Ross, Alasdair
core  

Home - About - Disclaimer - Privacy